CSHL Single Cell Biology Core


Spatial Biology
@
CSHL
Services
We are proud to offer the following spatial biology services:
​​
In Situ Profiling
10X Genomics Xenium
-
Off-the-shelf panels of 350-00 target genes
-
Customizable add-on panels of 50-100 genes
-
Co-stain with H&E and immunofluorescence
-
1cm x 2cm imaging area per slide
-
mouse and human panels
​
Spatial Transcriptomics
10X Genomics Visium FFPE
-
Whole-transcriptome analysis
-
6mm x 6mm tissue sections, 4 per slide
-
100um center-to-center spot resolution
-
Co-stain with H&E or immunofluorescence
-
mouse and human panels
10X Genomics Visium CytAssist
-
Transfer existing, imaged slide sections to Visium
-
No need to cutting & sectioning
​
Multiplexed Immunofluorescence
Lunaphore COMET
-
Off-the-shelf pre-optimized panels of ~13 target proteins for Human and Mouse
-
Customize your own panel of up to 40 antibodies or add on to existing panels
-
12.5 x 12.5 mm imaging area per slide
-
Co-stain with H&E
​

Getting Started With Spatial
Pair the right sample with the right assay:
​Both Xenium and Visium assays require tissue to have high quality RNA but depending on the assay FFPE blocks, Fresh Frozen blocks, or pre cut slides can be used as input​