Publications

Regan, C., Preall, J. (August 2022) Practical Considerations for Single-Cell Genomics. Curr Protoc, 2 (8). e498. ISSN 2691-1299

Delgado, A. P., Nemajerova, A., Rao, M., Li, J., Marchenko, N., Preall, J., Moll, U. M., Egeblad, M., Powers, S. (May 2022) Single-cell genomic analysis of triple-negative breast cancer fibroblasts uncovers evolutionarily conserved features and potential therapeutic targets. bioRxiv. https://doi.org/10.1101/2022.05.05.490693

Wu, X. S., He, X., Ipsaro, J. J., Huang, Y., Preall, J. B., Ng, D., Shue, Y. T., Sage, J., Egeblad, M., Joshua-Tor, L., Vakoc, C. R. (May 2022) OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. ISSN 0028-0836

Gegenhuber, B., Wu, M.V., Bronstein, R., Tollkuhn, J. (May 2022) Gene regulation by gonadal hormone receptors underlies brain sex differences. Nature. ISSN 0028-0836

Bhatia, S., Kramer, M., Russo, S., Naik, P., Arun, G., Brophy, K., Andrews, P. A., Fan, C., Perou, C. M., Preall, J., Ha, T., Plenker, D., Tuveson, D. A., Rishi, A., Wilkinson, J. E., McCombie, W. R., Kostroff, K., Spector, D. L. (April 2022) Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics. Cancer Res, 82 (7). pp. 1174–1192. ISSN 1538-7445

Lin, X., Gaudino, S. J., Jang, K. K., Bahadur, T., Singh, A., Banerjee, A., Beaupre, M., Chu, T., Wong, H. T., Kim, C. K., Kempen, C., Axelrad, J., Huang, H., Khalid, S., Shah, V., Eskiocak, O., Parks, O. B., Berisha, A., McAleer, J. P., Good, M., Hoshino, M., Blumberg, R., Bialkowska, A. B., Gaffen, S. L., Kolls, J. K., Yang, V. W., Beyaz, S., Cadwell, K., Kumar, P. (January 2022). IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity, 55(2), 237–253.e8. ISSN 1074-7613

Hanasoge Somasundara, A. V., Moss, M. A., Feigman, M. J., Chen, C., Cyrill, S. L., Ciccone, M. F., Trousdell, M. C., Vollbrecht, M., Li, S., Kendall, J., Beyaz, S., Wilkinson, J. E., Dos Santos, C. O. (December 2021) Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis. Cell Reports, 37 (10). p. 110099. ISSN 2211-1247

Henry, S., Trousdell, M. C., Cyrill, S. L., Zhao, Y., Feigman, M. J., Bouhuis, J. M., Aylard, D. A., Siepel, A., Dos Santos, C. O. (May 2021) Characterization of Gene Expression Signatures for the Identification of Cellular Heterogeneity in the Developing Mammary Gland. Journal of Mammary Gland Biology and Neoplasia. ISSN 1083-3021

Steele, N. G., Biffi, G., Kemp, S. B., Zhang, Y., Drouillard, D., Syu, L., Hao, Y., Oni, T. E., Brosnan, E., Elyada, E., Doshi, A., Hansma, C., Espinoza, C., Abbas, A., The, S., Irizarry-Negron, V., Halbrook, C. J., Franks, N. E., Hoffman, M. T., Brown, K., Carpenter, E. S., Nwosu, Z. C., Johnson, C., Lima, F., Anderson, M. A., Park, Y., Crawford, H. C., Lyssiotis, C. A., Frankel, T. L., Rao, A., Bednar, F., Dlugosz, A. A., Preall, J. B., Tuveson, D. A., Allen, B. L., Pasca di Magliano, M. (April 2021) Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer. Clinical Cancer Research, 27 (7). pp. 2023-2037. ISSN 1078-0432

Xu, X., Crow, M., Rice, B. R., Li, F., Harris, B., Liu, L., Demesa-Arevalo, E., Lu, Z., Wang, L., Fox, N., Wang, X., Drenkow, J., Luo, A., Char, S. N., Yang, B., Sylvester, A. W., Gingeras, T. R., Schmitz, R. J., Ware, D., Lipka, A. E., Gillis, J., Jackson, D. (December 2020) Single-cell RNA sequencing of developing maize ears facilitates functional analysis and trait candidate gene discovery. Dev Cell, S1534- (20). pp. 31021-31022. ISSN 1534-5807

Somerville, T. D. D., Xu, Y., Wu, X. S., Maia-Silva, D., Hur, S. K., de Almeida, L. M. N., Preall, J. B., Koo, P. K., Vakoc, C. R. (May 2020) ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer. Proc Natl Acad Sci U S A, 117 (21). pp. 11471-11482. ISSN 0027-8424 (Print)0027-8424

Somerville, T. D. D., Biffi, G., DaBler-Plenker, J., Hur, S.K., He, X.-Y., Vance, K.E., Miyabayashi, K., Xu, Y., Maia-Silva, D., Klingbeil, O., Demerdash, O. E., Preall, J. B., Hollingsworth, M. A., Egeblad, M., Tuveson, D. A., Vakoc, C. R. (April 2020) Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. Elife, 9. e53381. ISSN 2050-084x (Public Dataset)

Chen, X., Sun, Y. C., Zhan, H., Kebschull, J. M., Fischer, S., Matho, K., Huang, Z. J., Gillis, J., Zador, A. M. (October 2019) High-Throughput Mapping of Long-Range Neuronal Projection Using In Situ Sequencing. Cell, 179 (3). 772-786.e19. ISSN 0092-8674 (Public Dataset)

Carter, J. A., Preall, J. B., Atwal, G. S. (October 2019) Bayesian Inference of Allelic Inclusion Rates in the Human T Cell Receptor Repertoire. Cell Syst, 9 (5). pp. 475-482. ISSN 2405-4712 (Public Dataset)

Carter, J. A., Preall, J. B., Grigaityte, K., Goldfless, S. J., Jeffery, E., Briggs, A. W., Vigneault, F., Atwal, G. S. (July 2019) Single T Cell Sequencing Demonstrates the Functional Role alpha beta TCR Pairing in Cell Lineage and Antigen Specificity. Frontiers in Immunology, 10. Article Number:1516. ISSN 1664-3224

Elyada, E., Bolisetty, M., Laise, P., Flynn, W. F., Courtois, E. T., Burkhart, R. A., Teinor, J. A., Belleau, P., Biffi, G., Lucito, M. S., Sivajothi, S., Armstrong, T. D., Engle, D. D., Yu, K. H., Hao, Y., Wolfgang, C. L., Park, Y., Preall, J., Jaffee, E. M., Califano, A., Robson, P., Tuveson, D. A. (June 2019) Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts. Cancer Discov, 9 (8). pp. 1102-1123. ISSN 2159-8274

Biffi, G., Oni, T. E., Spielman, B., Hao, Y., Elyada, E., Park, Y., Preall, J., Tuveson, D. A. (October 2018) IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma. Cancer Discov, 9 (2). pp. 282-301. ISSN 2159-8274